Saturday, 24 March 2012

Lab1: Principles and use of microscope

Name : Kong Siao Thung
Matric No. : 111372
Lab 1: Principles and use of microscope

Introduction

1.1 Setting up and using the microscope
In order to be seen, microorganisms need to be magnified. Despite advances in other area of microscopy (for example, the electron microscope), the light microscope is still the instrument most frequently used for viewing microorganisms.

1.2 Examination of cells
Because of their extreme minuteness, bacteria are not generally studied with the low-power or high power-power dry objectives. Instead they are stained and observed with the oil immersion objective.
The wet mount methods enable you to study the sizes and shapes of living microorganisms (drying or staining microorganisms distort them). It also enables you to determine if cells are motile. The wet mount method is quick and easy, and does not require special equipment.

Objective

1.1 Setting up and using the microscope
Learn to use a simple bright-field microscope correctly

1.2 Examination of cells
a) To provide an experience in the use of microscope.
b) To illustrate the diversity of cells and microorganisms.

Results : 1.1) Stained Cells
Typical Bacillus ( 40x Magnification)
































Typical Bacillus ( 100x Magnification)






























Typical Bacillus ( 400x Magnification)



































Typical Bacillus ( 1000x Magnification)



























Discussions:

By using the magnification of 40x, 100x, 400x, 1000x, we are able to see a very clear image of the Typical Bacillus. The specimen is observed from the lowest 40x magnification to the highest magnification which is 100x. We can see clearly the morphology of typical bacillus.

The colony morphology of Typical Bacillus:
a)      Colour:  Red
b)      Shape:  irregular shape
c)       Size: Punctiform
d)      Texture: Moist
e)      Surface: Smooth and shiny


Results: 1.2) Wet mount

Lactobacillus fementum (1000x Macnification)





















Yeast (Saccharomyces cerevisiae) (1000x Magnification)

































Discussions:


The wet mount method was used to determine size and shape of living microorganisms. We need to use the aseptic technique which is the flame sterilization to sterilize the opening of vessel and inoculating loops. This technique is used to avoid contamination of the sample. Besides that, oil immersion is used to view individual cell or the details of the striations of muscle. It is nearly impossible to view living, motile protest at a magnification of 1000x, except for the very small and slow one.

The morphology of Lactobacillus fermentum:
f)       Colour: Grey
g)      Shape: Rod shape
h)      Size: Punctiform
i)        Texture: Moist
j)        Surface: Shiny and smooth

The colony morphology of Saccharomyces cerevisiae:
a)      Colour: Brownish yellow
b)      Shape: Circular
c)       Size: 5–10 micrometres in diameter
d)      Texture: Moist
e)      Surface: Rough, dull, wrinkled

Conclusions:

1.1 Setting up and using the microscope
In conclusion, we can clearly observed the image of the specimen by using 40x magnification. For the 1000x magnification, a smaller specimen will get a clearer view.

1.2 Examination of cells
        In conclusion, a cleary image of cells can be seen clearly under 1000x magnification with the aid of oil immersion.

References:

~David B. Jansma, REGULATlON AND VARlATlON OF SUBUNITS OF RNA POLYMERASE II IN SACCHAROMYCES CEREVISIAE
~ Golden, David M.; Jay, James M.; Martin J. Loessner (2005). Modern food microbiology. Berlin: Springer. p. 179
~Kandler O., Stetter K., Kohl R. 1980. Lactobacillus reuteri sp. nov. a new species of heterofermentative lactobacilli. Zbl. Bakt. Hyg. Abt. Orig. C1:264-269
~http://www.connecticutvalleybiological.com/bacteria-typical-bacillus-c-1379_1384.html

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